Reversibly contractile nuclear matrix. Its isolation, structure, and composition.
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چکیده
منابع مشابه
A REVERSIBLY CONTRACTILE NUCLEAR MATRIX Its Isolation, Structure, and Composition
From Tetrahymena macronuclei we have isolated a reversibly contractile nucleoskeleton, i.e., an "expanded" nuclear matrix which reversibly contracts when the total concentration of the bivalent cations, Ca and Mg (3:2), is decreased to 5 mM or increased to 125 raM. During contraction the average diameter of the expanded matrix becomes reduced by about 24%; this corresponds to a volume contracti...
متن کاملReversibly contractile nuclear matrix. Its isolation, structure, and composition
From Tetrahymena macronuclei we have isolated a reversibly contractile nucleo-skeleton, i.e., an "expanded" nuclear matrix which reversibly contracts when the total concentration of the bivalent cations, Ca and Mg (3:2), is decreased to 5 mM or increased to 125 mM. During contraction the average diameter of the expanded matrix becomes reduced by about 24%; this corresponds to a volume contracti...
متن کاملan overview to the structure and function of nuclear matrix
although the genome is defined by its primary sequence, its functional properties, are determined by far more complex mechanisms and depend on multiple layers of nuclear organization. the architecture of the nucleus includes two overlapping structures: the chromatin and a framework structure named the nuclear matrix. ultra-structural studies reveal that the nuclear matrix is a network consistin...
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A nuclear framework structure termed the nuclear matrix has been isolated and characterized. This matrix forms the major residual structure of isolated nuclei and consists largely of protein with smaller amounts of RNA, DNA, carbohydrate, and phospholipid. The nuclear matrix can be further resolved by combined treatment with DNase and RNase. The remaining nuclear protein structure, after extrac...
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Transient coronary occlusion (15 minutes) does not result in irreversible myocardial injury but is associated with a depression of contractile function sustained for several hours to days ("stunned myocardium"). The defect in the contractile process responsible for this phenomenon has been suggested to be causally related to a reduced energetic state, altered excitation or excitation-contractio...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1977
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.73.2.271